Metformin Arya 500

Metformin is indicated in patients with type 2 diabetes to control hyperglycemia that cannot be controlled by diet management, exercise, or weight reduction, or when insulin therapy is not required or feasible. It is used as monotherapy or as an adjunct to sulfonylureas or insulin when either alone does not achieve adequate glycemic control. It can be tried if primary or secondary failure of sulfonylureas occurs. However, caution and clinical judgment should be used when combining metformin with maximum doses of sulfonylureas for treating nonobese patients with type 2 diabetes who clearly are not responding to the sulfonylurease; insulin may be the preferred treatment in such cases.